Students will participate in the regional science expo that covers where they attend school. For example, a student who lives within the boundaries of the Beaverton School District but attends Jesuit High School will participate in the Portland Community College Science Expo. All high school students must qualify at a regional science expo in order to attend the Intel Northwest Science Expo. Traditionally the top third of high school projects from a regional fair will move on to Intel NWSE. High school students who are not in the defined area of any of the regional science expos must attend the Portland Community College Science Expo. Middle School students are encouraged to attend their regional fair, but may come directly to the state fair.

Aardvark Science Expo: Serves students enrolled in Oregon Episcopal School. Held in Portland.

Beaverton - Hillsboro Science Expo: Serves high school students enrolled in the Beaverton and Hillsboro school districts. Held in Hillsboro.

Central Western Oregon Science Expo: Serves Yamhill, Marion, Linn, Benton, Tillamook, and Polk counties, Lane county east of the Coast range. Held in Albany.

CREST-Jane Goodall Science Symposium: Serves high school students enrolled in the West Linn - Wilsonville school district. Held in Wilsonville.

Gresham Science Expo (At-Large): Serves counties not covered by other regional fairs. Location to be determined.

High Desert Science Expo: Serves high school students in Deschutes, Crook, Jefferson, Wheeler and Grant counties.

Portland Public Schools Science Expo: Serves high school students enrolled in the Portland Public Schools. Held in Portland.

Southwestern Oregon Regional Science Expo: Serves Josephine, Jackson, Douglas, Curry, Coos, Lake and Klamath counties, and Lane county west of the Coast Range mountains. Held in Coos Bay.